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Xylazine 100 mg/mL Injection
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Analgesic, sedative and muscle relaxant for use in horses.
Size: 50 mL vial
Dosage and Administration
Use the contents within 3 months of first broaching the vial. Discard the unused portion.
Horses
Vary dosage schedule according to circumstances and depth and duration of sedation required.
Intravenous administration usually gives a more rapid onset of effect, but the duration is shorter than with intramuscular administration.
Xylazine may be used alone or combined with other sedatives, analgesics and anaesthetics to produce the desired effect from mild sedation to heavy
sedation to (in combination with ketamine) full surgical anaesthesia.
Mild Sedation | Intravenous (slow): 0.25 - 0.5 mL per 100 kg bodyweight (0.25 - 0.5 mg per kg). |
Heavy Sedation |
Intravenous (slow): 1.1 mL per 100 kg bodyweight (1.1 mg per kg). Intramuscular: 2.2 mL per 100 kg bodyweight (2.2 mg per kg). |
Spasmodic Colic |
Xylazine may be used as a sedative/analgesic in spasmodic (hypermotility) colic. However, it is contraindicated in cases of obstructive colic or ileus as xylazine will further reduce gut motility. In early stages of presentation of colic, it may be difficult to differentiate between spasmodic colic and one that will progress to obstructive colic. Therefore, considerable care should be taken in diagnosis and alternative analgesia used if diagnosis is in doubt. Intravenous (slow): 0.5 mL per 100 kg bodyweight (0.5 mg per kg). This dose will provide analgesia for about 20 minutes. Other α-2 adrenoceptor agonists, may provide more powerful and longer lasting sedation and analgesic effects. In cases of moderate to severe spasmodic colic, profound analgesia can be achieved by combining butorphanol with xylazine (0.5 mg per kg). |
Active Constituent(s)
Contraindications
- Intra-arterial administration
- Use in horses with obstructive colic or ileus
- Use in mares in last trimester of pregnancy
- Concurrent administration with adrenaline
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